Issue

Vol. 18 (2026)

Biomass-Based Antifouling Coatings: Mechanisms, Materials, Applications, and Emerging Sustainable Strategies

https://doi.org/10.1007/s40820-026-02137-4
Yudi Wei
Division of Machine Elements, Luleå University of Technology, 97187 Luleå, Sweden
Dominik Maršík
Biochemical Process Engineering, Division of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 971‑87 Luleå, Sweden
Petter Paulsen Thoresen
Biochemical Process Engineering, Division of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 971‑87 Luleå, Sweden
Leonidas Matsakas
Biochemical Process Engineering, Division of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 971‑87 Luleå, Sweden
Yijun Shi
Division of Machine Elements, Luleå University of Technology, 97187 Luleå, Sweden

Corresponding Author: Yijun Shi

yijun.shi@ltu.se

Nano-Micro Letters, Vol. 18 (2026), Article Number: 305

Abstract

Biofouling remains a critical challenge across marine, medical, and industrial sectors, driving the need for sustainable and eco-friendly antifouling coatings. Biomass-based materials, including lignin, tannins, betaines, polysaccharides, and proteins, have emerged as promising candidates due to their biocompatibility, biodegradability, and diverse antifouling mechanisms. These materials inhibit biofouling through mechanisms such as hydration layer formation, surface charge repulsion, hydrophobic foul-release, and biocidal effects, offering effective resistance to protein adsorption, bacterial attachment, and biofilm formation. This review provides a comprehensive overview of recent advancements in biomass-based antifouling coatings, focusing on their antifouling mechanisms, synthesis methods, and applications. Key challenges concerning mechanical durability and scalability are explored, along with potential approaches to enhance the development of sustainable antifouling technologies.


Highlights:
1 This review systematically categorizes biomass-based antifouling coatings based on lignin, tannins, betaines, polysaccharides and proteins, highlighting how their intrinsic chemistries contribute to antifouling interfaces.
2 The review clarifies how hydration layers, foul-release interfaces, surface charge regulation and biocidal actions collectively contribute to antifouling performance.
3 Key chemical and physical crosslinking strategies are compared to highlight their roles in enhancing mechanical integrity and long-term stability.
4 Critical bottlenecks in durability, adhesion, validation and scalability are identified, and potential routes for future technological development are outlined.

Keywords

Biomass-based antifouling coatings Antifouling mechanisms Crosslinking strategies Marine and biomedical applications
Wei, Yudi, Dominik Maršík, Petter Paulsen Thoresen, Leonidas Matsakas, and Yijun Shi. 2026. “Biomass-Based Antifouling Coatings: Mechanisms, Materials, Applications, and Emerging Sustainable Strategies”. Nano-Micro Letters 18 (March):305. https://doi.org/10.1007/s40820-026-02137-4.
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References
  1. Q. Qiu, Y. Gu, Y. Ren, H. Ding, C. Hu et al., Research progress on eco-friendly natural antifouling agents and their antifouling mechanisms. Chem. Eng. J. 495, 153638 (2024). https://doi.org/10.1016/j.cej.2024.153638
  2. S. Li, K. Feng, J. Li, Y. Li, Z. Li et al., Marine antifouling strategies: emerging opportunities for seawater resource utilization. Chem. Eng. J. 486, 149859 (2024). https://doi.org/10.1016/j.cej.2024.149859
  3. X. Li, R. Zhang, J. Zhang, Q. Li, Z. Yu et al., Harnessing biofilm scaffold for structurally adaptative slippery surfaces with integrated antifouling and anticorrosion properties. Angew. Chem. Int. Ed. 64(23), e202503295 (2025). https://doi.org/10.1002/anie.202503295
  4. N. Hadžić, I. Gatin, T. Uroić, V. Ložar, Biofouling dynamic and its impact on ship powering and dry-docking. Ocean Eng. 245, 110522 (2022). https://doi.org/10.1016/j.oceaneng.2022.110522
  5. A. Farkas, S. Song, N. Degiuli, I. Martić, Y.K. Demirel, Impact of biofilm on the ship propulsion characteristics and the speed reduction. Ocean Eng. 199, 107033 (2020). https://doi.org/10.1016/j.oceaneng.2020.107033
  6. S. Liu, Y.H. Kee, B. Shang, A. Papanikolaou, Assessment of the economic, environmental and safety impact of biofouling on a ship’s hull and propeller. Ocean Eng. 285, 115481 (2023). https://doi.org/10.1016/j.oceaneng.2023.115481
  7. A. Farkas, N. Degiuli, I. Martić, I. Ančić, Energy savings potential of hull cleaning in a shipping industry. J. Clean. Prod. 374, 134000 (2022). https://doi.org/10.1016/j.jclepro.2022.134000
  8. M.P. Schultz, J.A. Bendick, E.R. Holm, W.M. Hertel, Economic impact of biofouling on a naval surface ship. Biofouling 27(1), 87–98 (2011). https://doi.org/10.1080/08927014.2010.542809
  9. E. Castillo, R.A. Rojas-Fermin, Y. Reyes, C. Blanco, A.M. Villegas et al., A nationwide survey of infection prevention and control and high-level disinfection and sterilization practices in the Dominican Republic. Open Forum Infect. Dis. (2025). https://doi.org/10.1093/ofid/ofae631.605
  10. P. Elumalai, X. Gao, J. Cui, A.S. Kumar, P. Dhandapani et al., Biofilm formation, occurrence, microbial communication, impact and characterization methods in natural and anthropic systems: a review. Environ. Chem. Lett. 22(3), 1297–1326 (2024). https://doi.org/10.1007/s10311-024-01715-5
  11. X. Liu, L. Zou, B. Li, P. Di Martino, D. Rittschof et al., Chemical signaling in biofilm-mediated biofouling. Nat. Chem. Biol. 20(11), 1406–1419 (2024). https://doi.org/10.1038/s41589-024-01740-z
  12. P. Vuong, A. McKinley, P. Kaur, Understanding biofouling and contaminant accretion on submerged marine structures. Npj Mater. Degrad. 7, 50 (2023). https://doi.org/10.1038/s41529-023-00370-5
  13. J.T. Antunes, A.G.G. Sousa, J. Azevedo, A. Rego, P.N. Leão et al., Distinct temporal succession of bacterial communities in early marine biofilms in a Portuguese Atlantic Port. Front. Microbiol. 11, 1938 (2020). https://doi.org/10.3389/fmicb.2020.01938
  14. H. Dang, C.R. Lovell, Microbial surface colonization and biofilm development in marine environments. Microbiol Mol Biol Rev 80(1), 91–138 (2015). https://doi.org/10.1128/MMBR.00037-15
  15. M. Grzegorczyk, S.J. Pogorzelski, A. Pospiech, K. Boniewicz-Szmyt, Monitoring of marine biofilm formation dynamics at submerged solid surfaces with multitechnique sensors. Front. Mar. Sci. 5, 363 (2018). https://doi.org/10.3389/fmars.2018.00363
  16. A.A. Balqadi, A.J. Salama, S. Satheesh, Microfouling development on artificial substrates deployed in the central Red Sea. Oceanol. 60(2), 219–231 (2018). https://doi.org/10.1016/j.oceano.2017.10.006
  17. R.D. Monds, G.A. O’Toole, The developmental model of microbial biofilms: ten years of a paradigm up for review. Trends Microbiol. 17(2), 73–87 (2009). https://doi.org/10.1016/j.tim.2008.11.001
  18. H.-C. Flemming, S. Wuertz, Bacteria and Archaea on Earth and their abundance in biofilms. Nat. Rev. Microbiol. 17(4), 247–260 (2019). https://doi.org/10.1038/s41579-019-0158-9
  19. K. Sauer, P. Stoodley, D.M. Goeres, L. Hall-Stoodley, M. Burmølle et al., The biofilm life cycle: expanding the conceptual model of biofilm formation. Nat. Rev. Microbiol. 20(10), 608–620 (2022). https://doi.org/10.1038/s41579-022-00767-0
  20. L.C. Simões, I.B. Gomes, H. Sousa, A. Borges, M. Simões, Biofilm formation under high shear stress increases resilience to chemical and mechanical challenges. Biofouling 38(1), 1–12 (2022). https://doi.org/10.1080/08927014.2021.2006189
  21. M.I. Hasan, S. Aggarwal, Matrix matters: how extracellular substances shape biofilm structure and mechanical properties. Colloids Surf. B Biointerfaces 246, 114341 (2025). https://doi.org/10.1016/j.colsurfb.2024.114341
  22. L.R. Hmelo, Quorum sensing in marine microbial environments. Annu. Rev. Mar. Sci. 9, 257–281 (2017). https://doi.org/10.1146/annurev-marine-010816-060656
  23. L. Karygianni, Z. Ren, H. Koo, T. Thurnheer, Biofilm matrixome: extracellular components in structured microbial communities. Trends Microbiol. 28(8), 668–681 (2020). https://doi.org/10.1016/j.tim.2020.03.016
  24. F. Benhadda, A. Zykwinska, S. Colliec-Jouault, C. Sinquin, B. Thollas et al., Marine versus non-marine bacterial exopolysaccharides and their skincare applications. Mar. Drugs 21(11), 582 (2023). https://doi.org/10.3390/md21110582
  25. Y. Jiang, S. Liang, Q. Niu, C. Liu, G. Yu et al., Statistical investigation of marine bacterial extracellular polysaccharides: deciphering the interplay among environmental adaptation, species distribution, and biomedical potential. Mar. Life Sci. Technol. (2025). https://doi.org/10.1007/s42995-025-00283-z
  26. N. Sharma, M.S. Farooqi, K.K. Chaturvedi, S.B. Lal, M. Grover et al., The halophile protein database. Database (2014). https://doi.org/10.1093/database/bau114
  27. C. Rubiano-Labrador, C. Bland, G. Miotello, J. Armengaud, S. Baena, Salt stress induced changes in the exoproteome of the halotolerant bacterium Tistlia consotensis deciphered by proteogenomics. PLoS ONE 10(8), e0135065 (2015). https://doi.org/10.1371/journal.pone.0135065
  28. N.J. Russell, Adaptive modifications in membranes of halotolerant and halophilic microorganisms. J. Bioenerg. Biomembr. 21(1), 93–113 (1989). https://doi.org/10.1007/BF00762214
  29. B. Tuck, S.J. Salgar-Chaparro, E. Watkin, A. Somers, M. Forsyth et al., Extracellular DNA: a critical aspect of marine biofilms. Microorg 10(7), 1285 (2022). https://doi.org/10.3390/microorganisms10071285
  30. B. Tuck, E. Watkin, A. Somers, M. Forsyth, L.L. Machuca, Enhancing biocide efficacy: targeting extracellular DNA for marine biofilm disruption. Microorg 10(6), 1227 (2022). https://doi.org/10.3390/microorganisms10061227
  31. Y. Su, J.T. Yrastorza, M. Matis, J. Cusick, S. Zhao et al., Biofilms: formation, research models, potential targets, and methods for prevention and treatment. Adv. Sci. 9(29), 2203291 (2022). https://doi.org/10.1002/advs.202203291
  32. L. Kumar, M. Bisen, K. Harjai, S. Chhibber, S. Azizov et al., Advances in nanotechnology for biofilm inhibition. ACS Omega 8(24), 21391–21409 (2023). https://doi.org/10.1021/acsomega.3c02239
  33. Q. Zhang, Q. Ma, Y. Wang, H. Wu, J. Zou, Molecular mechanisms of inhibiting glucosyltransferases for biofilm formation in Streptococcus mutans. Int. J. Oral Sci. 13(1), 30 (2021). https://doi.org/10.1038/s41368-021-00137-1
  34. Y. Wang, Z. Bian, Y. Wang, Biofilm formation and inhibition mediated by bacterial quorum sensing. Appl. Microbiol. Biotechnol. 106(19), 6365–6381 (2022). https://doi.org/10.1007/s00253-022-12150-3
  35. Y. Qian, L. Zhang, N. Li, F. Dong, Z. Yang et al., A magnetic cloud bomb for effective biofilm eradication. Adv. Funct. Mater. 33(15), 2214330 (2023). https://doi.org/10.1002/adfm.202214330
  36. S. Pourhashem, A. Seif, F. Saba, E.G. Nezhad, X. Ji et al., Antifouling nanocomposite polymer coatings for marine applications: a review on experiments, mechanisms, and theoretical studies. J. Mater. Sci. Technol. 118, 73–113 (2022). https://doi.org/10.1016/j.jmst.2021.11.061
  37. H. Jin, L. Tian, W. Bing, J. Zhao, L. Ren, Bioinspired marine antifouling coatings: status, prospects, and future. Prog. Mater. Sci. 124, 100889 (2022). https://doi.org/10.1016/j.pmatsci.2021.100889
  38. A.M.C. Maan, A.H. Hofman, W.M. de Vos, M. Kamperman, Recent developments and practical feasibility of polymer-based antifouling coatings. Adv. Funct. Mater. 30(32), 2000936 (2020). https://doi.org/10.1002/adfm.202000936
  39. D. Anton, Surface-fluorinated coatings. Adv. Mater. 10(15), 1197–1205 (1998). https://doi.org/10.1002/(sici)1521-4095(199810)10:15<1197::aid-adma1197>3.3.co;2-6
  40. J. Lv, Y. Cheng, Fluoropolymers in biomedical applications: state-of-the-art and future perspectives. Chem. Soc. Rev. 50(9), 5435–5467 (2021). https://doi.org/10.1039/d0cs00258e
  41. H. Sun, X. He, C. Yuan, X. Bai, Research progress and performance enhancement strategies of marine antifouling hydrogel coatings. Prog. Org. Coat. 206, 109365 (2025). https://doi.org/10.1016/j.porgcoat.2025.109365
  42. M. Fu, Y. Liang, X. Lv, C. Li, Y.Y. Yang et al., Recent advances in hydrogel-based anti-infective coatings. J. Mater. Sci. Technol. 85, 169–183 (2021). https://doi.org/10.1016/j.jmst.2020.12.070
  43. M.S. Selim, S.A. El-Safty, M.A. Shenashen, S.A. Higazy, A. Elmarakbi, Progress in biomimetic leverages for marine antifouling using nanocomposite coatings. J. Mater. Chem. B 8(17), 3701–3732 (2020). https://doi.org/10.1039/C9TB02119A
  44. M. Li, W. Xiao, Z. Yin, Y. Chen, Y. Luo et al., Construction of a robust MOF-based superhydrophobic composite coating with the excellent performance in antifouling, drag reduction, and organic photodegradation. Prog. Org. Coat. 186, 108086 (2024). https://doi.org/10.1016/j.porgcoat.2023.108086
  45. W. He, X. Li, X. Dai, L. Shao, Y. Fu et al., Redox concomitant formation method for fabrication of Cu(I)-MOF/polymer composites with antifouling properties. Angew. Chem. Int. Ed. 63(44), e202411539 (2024). https://doi.org/10.1002/anie.202411539
  46. Z. Yu, X. Li, Z. Wang, Y. Fan, W. Zhao et al., Robust chiral metal-organic framework coatings for self-activating and sustainable biofouling mitigation. Adv. Mater. 36(45), e2407409 (2024). https://doi.org/10.1002/adma.202407409
  47. G. Lu, S. Tian, J. Li, Y. Xu, S. Liu et al., Fabrication of bio-based amphiphilic hydrogel coating with excellent antifouling and mechanical properties. Chem. Eng. J. 409, 128134 (2021). https://doi.org/10.1016/j.cej.2020.128134
  48. M. Shigrekar, V. Amdoskar, A review on recent progress and techniques used for fabricating superhydrophobic coatings derived from biobased materials. RSC Adv. 14(44), 32668–32699 (2024). https://doi.org/10.1039/D4RA04767B
  49. R. Guo, H. Shi, W. Wu, M. Du, Q. Zheng, Research advances in low surface energy antifouling coatings for ships with structural bionic properties. Polym. Adv. Technol. 36(3), e70146 (2025). https://doi.org/10.1002/pat.70146
  50. Z. Chen, Surface hydration and antifouling activity of zwitterionic polymers. Langmuir 38(15), 4483–4489 (2022). https://doi.org/10.1021/acs.langmuir.2c00512
  51. H. Yang, Y. Wang, L. Yao, J. Wang, H. Chen, Antifouling polymer coatings for bioactive surfaces. Langmuir 41(10), 6471–6496 (2025). https://doi.org/10.1021/acs.langmuir.4c04859
  52. Z. Wang, L. Scheres, H. Xia, H. Zuilhof, Developments and challenges in self-healing antifouling materials. Adv. Funct. Mater. 30(26), 1908098 (2020). https://doi.org/10.1002/adfm.201908098
  53. Q. Xin, Z. Ma, S. Sun, H. Zhang, Y. Zhang et al., Supramolecular self-healing antifouling coating for dental materials. ACS Appl. Mater. Interfaces 15(35), 41403–41416 (2023). https://doi.org/10.1021/acsami.3c09628
  54. B.N. Sahoo, P.J. Thomas, P. Thomas, M.M. Greve, Antibiofouling coatings for marine sensors: progress and perspectives on materials, methods, impacts, and field trial studies. ACS Sens. 10(3), 1600–1619 (2025). https://doi.org/10.1021/acssensors.4c02670
  55. K. Amoako, R. Ukita, K.E. Cook, Antifouling zwitterionic polymer coatings for blood-bearing medical devices. Langmuir 41(5), 2994–3006 (2025). https://doi.org/10.1021/acs.langmuir.4c04532
  56. S. Chen, L. Li, C. Zhao, J. Zheng, Surface hydration: principles and applications toward low-fouling/nonfouling biomaterials. Polymer 51(23), 5283–5293 (2010). https://doi.org/10.1016/j.polymer.2010.08.022
  57. R. Zhang, H. Lin, Z. Wang, S. Cheng, C. Li et al., Research progress on antimicrobial biomaterials. Macromol. Biosci. 25(9), e00239 (2025). https://doi.org/10.1002/mabi.202500239
  58. P.J. Molino, D. Yang, M. Penna, K. Miyazawa, B.R. Knowles et al., Hydration layer structure of biofouling-resistant nanops. ACS Nano 12(11), 11610–11624 (2018). https://doi.org/10.1021/acsnano.8b06856
  59. X.-W. Wang, J. Wang, Y. Yu, L. Yu, Y.-X. Wang et al., A polyzwitterion-based antifouling and flexible bilayer hydrogel coating. Compos. Part B Eng. 244, 110164 (2022). https://doi.org/10.1016/j.compositesb.2022.110164
  60. B.B. Berking, G. Poulladofonou, D. Karagrigoriou, D.A. Wilson, K. Neumann, Zwitterionic polymeric sulfur ylides with minimal charge separation open a new generation of antifouling and bactericidal materials. Angew. Chem. Int. Ed. 62(41), e202308971 (2023). https://doi.org/10.1002/anie.202308971
  61. Z. Zhao, C. Huang, H. Zeng, Zwitterion-conjugated protein coatings for enhanced antifouling in complex biofluids: underlying molecular interaction mechanisms. Langmuir 40(48), 25708–25716 (2024). https://doi.org/10.1021/acs.langmuir.4c03975
  62. J. Peng, K. Li, Y. Du, F. Yi, L. Wu et al., A robust mixed-charge zwitterionic polyurethane coating integrated with antibacterial and anticoagulant functions for interventional blood-contacting devices. J. Mater. Chem. B 11(33), 8020–8032 (2023). https://doi.org/10.1039/D3TB01443F
  63. Q. Li, L. Wang, L. Yu, C. Li, X. Xie et al., Polysaccharide-based coating with excellent antibiofilm and repeatable antifouling-bactericidal properties for treating infected hernia. Biomacromol 25(2), 1180–1190 (2024). https://doi.org/10.1021/acs.biomac.3c01175
  64. H. Yang, L. Qin, W. Zhao, F.J. Mawignon, H. Guo et al., Eco-friendly polysaccharide coatings for antifouling and drag-reduction and potential application for marine devices. Friction 12(4), 726–744 (2024). https://doi.org/10.1007/s40544-023-0797-8
  65. T. Gnanasampanthan, J.F. Karthäuser, S. Spöllmann, R. Wanka, H.-W. Becker et al., Amphiphilic alginate-based layer-by-layer coatings exhibiting resistance against nonspecific protein adsorption and marine biofouling. ACS Appl. Mater. Interfaces 14(14), 16062–16073 (2022). https://doi.org/10.1021/acsami.2c01809
  66. D. Yu, F. Ye, S. Dobretsov, J. Dutta, Antifouling activity of PEGylated chitosan coatings: impacts of the side chain length and encapsulated ZnO/Ag nanops. Int. J. Biol. Macromol. 281, 136316 (2024). https://doi.org/10.1016/j.ijbiomac.2024.136316
  67. S. Zhu, G. Fu, X. Sun, C. Gao, Cationic copolymer with amphiphilic side chain and hydrophobic siloxane/polycaprolactone main chain for marine antifouling coating. Langmuir 41(12), 8342–8352 (2025). https://doi.org/10.1021/acs.langmuir.5c00179
  68. H. Durand, A. Whiteley, P. Mailley, G. Nonglaton, Combining topography and chemistry to produce antibiofouling surfaces: a review. ACS Appl. Bio Mater. 5(10), 4718–4740 (2022). https://doi.org/10.1021/acsabm.2c00586
  69. Y. Xu, X. Luan, P. He, D. Zhu, R. Mu et al., Fabrication and functional regulation of biomimetic interfaces and their antifouling and antibacterial applications: a review. Small 20(21), e2308091 (2024). https://doi.org/10.1002/smll.202308091
  70. W. Yang, D. Yang, Z. Zhao, C. Huang, B. Yan et al., Hierarchically engineered triple-defensive antifouling coating with well-regulated structure for enhanced wastewater treatment. Adv. Funct. Mater. 35(16), 2420149 (2025). https://doi.org/10.1002/adfm.202420149
  71. M. Lu, P. Lu, S. Liu, Y. Peng, Z. Yang et al., Chitosan/acrylic rosin-based superhydrophobic coatings inspired by Pickering emulsion template and Lotus leaf surface structure for paper-based food packaging. Int. J. Biol. Macromol. 308, 142375 (2025). https://doi.org/10.1016/j.ijbiomac.2025.142375
  72. X. Zhu, D. Jańczewski, S. Guo, S.S.C. Lee, F.J. Parra Velandia et al., Polyion multilayers with precise surface charge control for antifouling. ACS Appl. Mater. Interfaces 7(1), 852–861 (2015). https://doi.org/10.1021/am507371a
  73. D.U. Lee, D.W. Kim, S.Y. Lee, D.Y. Choi, S.Y. Choi et al., Amino acid-mediated negatively charged surface improve antifouling and tribological characteristics for medical applications. Colloids Surf. B Biointerfaces 211, 112314 (2022). https://doi.org/10.1016/j.colsurfb.2021.112314
  74. D. Rana, T. Matsuura, Surface modifications for antifouling membranes. Chem. Rev. 110(4), 2448–2471 (2010). https://doi.org/10.1021/cr800208y
  75. M. Yang, P. Hadi, X. Yin, J. Yu, X. Huang et al., Antifouling nanocellulose membranes: how subtle adjustment of surface charge lead to self-cleaning property. J. Membr. Sci. 618, 118739 (2021). https://doi.org/10.1016/j.memsci.2020.118739
  76. J. Ruwoldt, F.H. Blindheim, G. Chinga-Carrasco, Functional surfaces, films, and coatings with lignin - a critical review. RSC Adv. 13(18), 12529–12553 (2023). https://doi.org/10.1039/d2ra08179b
  77. X. Song, J. Man, X. Zhang, J. Wang, Y. Zhang et al., Atomistic insights into the ionic response and mechanism of antifouling zwitterionic polymer brushes. Small 21(6), e2406233 (2025). https://doi.org/10.1002/smll.202406233
  78. B. Wang, H. Ye, B. Chen, P. Zu, G. Lu, L. Ma, H. Zhang, M. Sun, Y. Li, H. Liu, J. Wu, A rationally designed polymer brush/lubricant coating system for effective static and dynamic marine antifouling. Chem. Eng. J. 495, 153568 (2024). https://doi.org/10.1016/j.cej.2024.153568
  79. Y. Liu, Y. Liu, Y. Wu, F. Zhou, Tuning surface functions by hydrophilic/hydrophobic polymer brushes. ACS Nano 19(12), 11576–11603 (2025). https://doi.org/10.1021/acsnano.4c18335
  80. X. Song, J. Man, Y. Qiu, J. Wang, R. Li et al., Study of hydration repulsion of zwitterionic polymer brushes resistant to protein adhesion through molecular simulations. ACS Appl. Mater. Interfaces 16(14), 17145–17162 (2024). https://doi.org/10.1021/acsami.3c18546
  81. S. Kim, Z. Yang, J. Jakowski, P. Ganesh, S.T. Retterer, J.-M.Y. Carrillo, All-atom modeling and simulation of biopolymer interface: dual role of antifouling polymer brushes. Langmuir 41(37), 25816–25826 (2025). https://doi.org/10.1021/acs.langmuir.5c03882
  82. R. Jiang, X. Zhai, Y. Liu, J. Chen, S.-Y. Gui, H. Liu, Assembly of polysaccharide-based polymer brush for supramolecular hydrogel dressing. Int. J. Biol. Macromol. 277, 134105 (2024). https://doi.org/10.1016/j.ijbiomac.2024.134105
  83. S. Xing, Q. Wang, Y. He, L. Chen, Topology effects of poly(2-ethyl-2-oxazoline) brushes with various architectures for antifouling behavior under shear flow. Biomacromol 24(7), 3237–3245 (2023). https://doi.org/10.1021/acs.biomac.3c00298
  84. Y. Tang, Y. Liu, D. Zhang, J. Zheng, Perspectives on theoretical models and molecular simulations of polymer brushes. Langmuir 40(2), 1487–1502 (2024). https://doi.org/10.1021/acs.langmuir.3c03253
  85. F. Ma, X. Tang, Y. Chao, X. Wang, X. Zheng et al., Antifouling and bactericidal zwitterionic polymer coatings with synergistic inhibitory and killing properties. ACS Appl. Bio Mater. 8(2), 1635–1645 (2025). https://doi.org/10.1021/acsabm.4c01776
  86. S. Wang, B. Qiu, J. Shi, M. Wang, Quaternary ammonium antimicrobial agents and their application in antifouling coatings: a review. J. Coat. Technol. Res. 21(1), 87–103 (2024). https://doi.org/10.1007/s11998-023-00825-z
  87. S.S.A. Athukoralalage, N. Amiralian, Dual-functional surface coatings integrating antimicrobial and antibiofouling mechanisms: from material design to application landscapes. Mater. Horiz. 12(23), 9966–9993 (2025). https://doi.org/10.1039/D5MH01132A
  88. J. Fouilloux, S. Abbad-Andaloussi, V. Langlois, L. Dammak, E. Renard, Green physical modification of polypropylene fabrics by cross-linking chitosan with tannic acid and postmodification by quaternary ammonium grafting to improve antibacterial activity. ACS Appl. Bio Mater. 6(12), 5609–5620 (2023). https://doi.org/10.1021/acsabm.3c00785
  89. G. Sathishkumar, K. Gopinath, K. Zhang, E.-T. Kang, L. Xu et al., Recent progress in tannic acid-driven antibacterial/antifouling surface coating strategies. J. Mater. Chem. B 10(14), 2296–2315 (2022). https://doi.org/10.1039/D1TB02073K
  90. M.H. Dahanayake, S.S. Athukorala, A.C.A. Jayasundera, Recent breakthroughs in nanostructured antiviral coating and filtration materials: a brief review. RSC Adv. 12(26), 16369–16385 (2022). https://doi.org/10.1039/D2RA01567F
  91. H. Wei, Q. Yang, T. Zhu, H. Cao, K. Yang et al., Sulfobetaine zwitterionic/quaternary ammonium cationic copolymers as high-efficiency antifouling and bactericidal coatings for polyurethane substrates. Prog. Org. Coat. 191, 108441 (2024). https://doi.org/10.1016/j.porgcoat.2024.108441
  92. A.B. Asha, Y.-Y. Peng, Q. Cheng, K. Ishihara, Y. Liu et al., Dopamine assisted self-cleaning, antifouling, and antibacterial coating via dynamic covalent interactions. ACS Appl. Mater. Interfaces 14(7), 9557–9569 (2022). https://doi.org/10.1021/acsami.1c19337
  93. X. Huang, X. Bao, Z. Wang, Q. Hu, A novel silver-loaded chitosan composite sponge with sustained silver release as a long-lasting antimicrobial dressing. RSC Adv. 7(55), 34655–34663 (2017). https://doi.org/10.1039/C7RA06430F
  94. M. Gouda, M.M. Khalaf, M.F. Abou Taleb, H.M. Abd El-Lateef, Fabrication of silver nanops loaded Acacia gum/chitosan nanogel to coat the pipe surface for sustainable inhibiting microbial adhesion and biofilm growth in water distribution systems. Int. J. Biol. Macromol. 262, 130085 (2024). https://doi.org/10.1016/j.ijbiomac.2024.130085
  95. A. Aradmehr, V. Javanbakht, A novel biofilm based on lignocellulosic compounds and chitosan modified with silver nanops with multifunctional properties: synthesis and characterization. Colloids Surf. A Physicochem. Eng. Aspects 600, 124952 (2020). https://doi.org/10.1016/j.colsurfa.2020.124952
  96. K.K. Patel, M. Tripathi, N. Pandey, A.K. Agrawal, S. Gade et al., Alginate lyase immobilized chitosan nanops of ciprofloxacin for the improved antimicrobial activity against the biofilm associated mucoid P. aeruginosa infection in cystic fibrosis. Int. J. Pharm. 563, 30–42 (2019). https://doi.org/10.1016/j.ijpharm.2019.03.051
  97. D. Yang, K. Gao, Y. Bai, L. Lei, T. Jia et al., Microfluidic synthesis of chitosan-coated magnetic alginate microps for controlled and sustained drug delivery. Int. J. Biol. Macromol. 182, 639–647 (2021). https://doi.org/10.1016/j.ijbiomac.2021.04.057
  98. P. Ran, B. Qiu, H. Zheng, S. Xie, G. Zhang et al., On-demand bactericidal and self-adaptive antifouling hydrogels for self-healing and lubricant coatings of catheters. Acta Biomater. 186, 215–228 (2024). https://doi.org/10.1016/j.actbio.2024.07.055
  99. Y. Jia, Y. Zhao, H. Zhang, Bioinspired self-adhesive multifunctional lubricated coating for biomedical implant applications. ACS Appl. Bio Mater. 7(7), 4307–4322 (2024). https://doi.org/10.1021/acsabm.4c00144
  100. B. Kaczmarek, A. Sionkowska, J. Kozlowska, A.M. Osyczka, New composite materials prepared by calcium phosphate precipitation in chitosan/collagen/hyaluronic acid sponge cross-linked by EDC/NHS. Int. J. Biol. Macromol. 107, 247–253 (2018). https://doi.org/10.1016/j.ijbiomac.2017.08.173
  101. M. Zheng, X. Wang, Y. Chen, O. Yue, Z. Bai et al., A review of recent progress on collagen-based biomaterials. Adv. Healthc. Mater. 12(16), 2202042 (2023). https://doi.org/10.1002/adhm.202202042
  102. Z. Zhang, B. Weng, Z. Hu, Z. Si, L. Li et al., Chitosan-iodine complexes: preparation, characterization, and antibacterial activity. Int. J. Biol. Macromol. 260, 129598 (2024). https://doi.org/10.1016/j.ijbiomac.2024.129598
  103. A. Hautmann, D. Kedilaya, S. Stojanović, M. Radenković, C.K. Marx et al., Free-standing multilayer films as growth factor reservoirs for future wound dressing applications. Biomater. Adv. 142, 213166 (2022). https://doi.org/10.1016/j.bioadv.2022.213166
  104. J. Zhang, M. Wu, P. Peng, J. Liu, J. Lu et al., “Self-defensive” antifouling zwitterionic hydrogel coatings on polymeric substrates. ACS Appl. Mater. Interfaces 14(50), 56097–56109 (2022). https://doi.org/10.1021/acsami.2c17272
  105. A.S. Imbia, A. Ounkaew, X. Mao, H. Zeng, Y. Liu et al., Tannic acid-based coatings containing zwitterionic copolymers for improved antifouling and antibacterial properties. Langmuir 40(7), 3549–3558 (2024). https://doi.org/10.1021/acs.langmuir.3c03237
  106. S. Basak, P. Singh, A. Weller, F.B. Kadumudi, P.J. Kempen et al., Cost-effective and eco-friendly sprayable nanogels (ZC-CSNG) for multifunctional wound dressing applications. Chem. Eng. J. 503, 158312 (2025). https://doi.org/10.1016/j.cej.2024.158312
  107. M. Sadeghi-Shapourabadi, M. Robert, S. Elkoun, A study of the influence of sodium alginate molecular weight and its crosslinking on the properties of potato peel waste-based films. Appl. Sci. 15(12), 6385 (2025). https://doi.org/10.3390/app15126385
  108. J.C. de Haro, E. Tatsi, L. Fagiolari, M. Bonomo, C. Barolo et al., Lignin-based polymer electrolyte membranes for sustainable aqueous dye-sensitized solar cells. ACS Sustain. Chem. Eng. 9(25), 8550–8560 (2021). https://doi.org/10.1021/acssuschemeng.1c01882
  109. X. Zhao, P. Zhao, D. Cao, J. Xiang, K. Li et al., Cross-linked cellulose acetate membrane with mixed-charge feature: a new approach to antifouling ultrafiltration membrane for drinking water. J. Membr. Sci. 718, 123680 (2025). https://doi.org/10.1016/j.memsci.2024.123680
  110. Z. Zhang, G. Sèbe, Y. Hou, J. Wang, J. Huang et al., Grafting polymers from cellulose nanocrystals via surface-initiated atom transfer radical polymerization. J. Appl. Polym. Sci. 138(48), 51458 (2021). https://doi.org/10.1002/app.51458
  111. J. Wang, L. Wang, H. Yu, Zain-ul-Abdin, Y. Chen et al., Recent progress on synthesis, property and application of modified chitosan: an overview. Int. J. Biol. Macromol. 88, 333–344 (2016). https://doi.org/10.1016/j.ijbiomac.2016.04.002
  112. S. Wang, K. Ren, M. Zhang, L. Shen, G. Zhou et al., Self-adhesive, strong antifouling, and mechanically reinforced methacrylate hyaluronic acid cross-linked carboxybetaine zwitterionic hydrogels. Biomacromol 25(1), 474–485 (2024). https://doi.org/10.1021/acs.biomac.3c01088
  113. J. Jeong, J. Do, S.M. Kang, Polydopamine-mediated, amphiphilic poly(carboxybetaine methacrylamide-r-trifluoroethyl methacrylate) coating with resistance to marine diatom adhesion and silt adsorption. Adv. Mater. Interfaces 11(11), 2300871 (2024). https://doi.org/10.1002/admi.202300871
  114. C. Huang, P. Huang, W. Yang, J. Liu, H. Zeng, Co-hydrolyzed bio-inspired antifouling coatings for functional membranes in oily wastewater treatment. J. Colloid Interface Sci. 699(2), 138197 (2025). https://doi.org/10.1016/j.jcis.2025.138197
  115. S. Wu, K. Yan, B. He, Y. Wang, S. Xue et al., Preparation of tannic acid based zwitterionic polymer functionalized coating on glass surface for antibacterial and antifouling applications. Prog. Org. Coat. 194, 108578 (2024). https://doi.org/10.1016/j.porgcoat.2024.108578
  116. T. Elschner, F. Obst, T. Heinze, Furfuryl- and maleimido polysaccharides: synthetic strategies toward functional biomaterials. Macromol. Biosci. 18(11), e1800258 (2018). https://doi.org/10.1002/mabi.201800258
  117. S. Liu, R. Chen, Q. Liu, J. Liu, J. Zhu et al., Schiff base modified polyurethane coating with enhanced mechanical property for marine antifouling application. Prog. Org. Coat. 203, 109138 (2025). https://doi.org/10.1016/j.porgcoat.2025.109138
  118. M. Yan, X. Lan, W. Zhao, Self-renewal poly-Schiff base/gallium-based liquid metal composite coatings triggered via water for superior antimicrobial performance under water. Prog. Org. Coat. 186, 108075 (2024). https://doi.org/10.1016/j.porgcoat.2023.108075
  119. A.M. Youssef Moustafa, M.M. Fawzy, M.S. Kelany, Y.A. Hassan, R.F.M. Elsharaawy et al., Synthesis of new quaternized chitosan Schiff bases and their N-alkyl derivatives as antimicrobial and anti-biofilm retardants in membrane technology. Int. J. Biol. Macromol. 267(Pt 2), 131635 (2024). https://doi.org/10.1016/j.ijbiomac.2024.131635
  120. Z. Shan, J. Huang, Y. Huang, Y. Zhou, Y. Li, Glutaraldehyde crosslinked ternary carboxymethylcellulose/polyvinyl alcohol/polyethyleneimine film with enhanced mechanical properties, water resistance, antibacterial activity, and UV-shielding ability without any UV absorbents. Int. J. Biol. Macromol. 277, 134563 (2024). https://doi.org/10.1016/j.ijbiomac.2024.134563
  121. E. Bahramzadeh, E. Yilmaz, S. Sheidaei, R. Nosrati, Glutaraldehyde-crosslinked chitosan-graft-poly(N-hydroxyethyl acrylamide) films: synthesis, characterization, and application as Fe3+ adsorbent. Int. J. Biol. Macromol. 321, 146343 (2025). https://doi.org/10.1016/j.ijbiomac.2025.146343
  122. Y. Yi, Y. Zhang, B. Mansel, Y.-N. Wang, S. Prabakar et al., Effect of dialdehyde carboxymethyl cellulose cross-linking on the porous structure of the collagen matrix. Biomacromol 23(4), 1723–1732 (2022). https://doi.org/10.1021/acs.biomac.1c01641
  123. Y. Ou, M. Tian, Advances in multifunctional chitosan-based self-healing hydrogels for biomedical applications. J. Mater. Chem. B 9(38), 7955–7971 (2021). https://doi.org/10.1039/D1TB01363G
  124. L. Deng, K. Ou, J. Shen, B. Wang, S. Chen et al., Double cross-linked chitosan/bacterial cellulose dressing with self-healable ability. Gels 9(10), 772 (2023). https://doi.org/10.3390/gels9100772
  125. P. Tordi, F. Ridi, P. Samorì, M. Bonini, Cation-alginate complexes and their hydrogels: a powerful toolkit for the development of next-generation sustainable functional materials. Adv. Funct. Mater. 35(9), 2416390 (2025). https://doi.org/10.1002/adfm.202416390
  126. Y. Xiong, D. Hu, L. Huang, Z. Fang, H. Jiang et al., Ultra-high strength sodium alginate/PVA/PHMB double-network hydrogels for marine antifouling. Prog. Org. Coat. 187, 108175 (2024). https://doi.org/10.1016/j.porgcoat.2023.108175
  127. Y. Li, Y. Miao, L. Yang, Y. Zhao, K. Wu et al., Recent advances in the development and antimicrobial applications of metal-phenolic networks. Adv. Sci. 9(27), 2202684 (2022). https://doi.org/10.1002/advs.202202684
  128. G. Fan, J. Cottet, M.R. Rodriguez-Otero, P. Wasuwanich, A.L. Furst, Metal-phenolic networks as versatile coating materials for biomedical applications. ACS Appl. Bio Mater. 5(10), 4687–4695 (2022). https://doi.org/10.1021/acsabm.2c00136
  129. Q. Liu, C. Xu, L. Pang, X. Xiong, H. Zhou et al., CuO2 and tannic acid mediated synergistic antimicrobial and antifouling coatings. Chem. Eng. J. 522, 167589 (2025). https://doi.org/10.1016/j.cej.2025.167589
  130. G. Yan, G. Chen, Z. Peng, Z. Shen, X. Tang et al., The cross-linking mechanism and applications of catechol–metal polymer materials. Adv. Mater. Interfaces 8(19), 2100239 (2021). https://doi.org/10.1002/admi.202100239
  131. S. Xie, T. Liu, H. Wen, G. Du, H. Yang et al., Wood bonding properties of cellulose cross-linked with a synthesized branched epoxy and enhanced by interfacial covalent bond. Cellulose 31(2), 1175–1187 (2024). https://doi.org/10.1007/s10570-023-05679-7
  132. S. Chandna, M.C.A. Olivares, E. Baranovskii, G. Engelmann, A. Böker et al., Lignin upconversion by functionalization and network formation. Angew. Chem. Int. Ed. 63(8), e202313945 (2024). https://doi.org/10.1002/anie.202313945
  133. M. Kang, H. Liang, Y. Hu, Y. Wei, D. Huang, Gelatin-based hydrogels with tunable network structure and mechanical property for promoting osteogenic differentiation. Int. J. Biol. Macromol. 281, 136312 (2024). https://doi.org/10.1016/j.ijbiomac.2024.136312
  134. Z. Rashedi, R. Mawhinney, W. Gao, A. Salaghi, P. Fatehi, Crosslinked lignin starch copolymer as a sustainable and thermally stable drilling fluid controller. Carbohydr. Polym. 350, 123044 (2025). https://doi.org/10.1016/j.carbpol.2024.123044
  135. T.A. Trinh, T.L. Nguyen, J. Kim, Lignin-based antioxidant hydrogel patch for the management of atopic dermatitis by mitigating oxidative stress in the skin. ACS Appl. Mater. Interfaces 16(26), 33135–33148 (2024). https://doi.org/10.1021/acsami.4c05523
  136. X. Teng, H. Xu, W. Song, J. Shi, J. Xin et al., Preparation and properties of hydrogels based on PEGylated lignosulfonate amine. ACS Omega 2(1), 251–259 (2017). https://doi.org/10.1021/acsomega.6b00296
  137. Z. Jiang, S. Zu, C. Li, J. Pang, Research progress on lignin-based epoxy resins: a green and sustainable path from biomass to new materials. Polym. Eng. Sci. 65(11), 5669–5690 (2025). https://doi.org/10.1002/pen.70114
  138. D. Wang, J. Zhao, P. Claesson, P. Christakopoulos, U. Rova et al., A strong enhancement of corrosion and wear resistance of polyurethane-based coating by chemically grafting of organosolv lignin. Mater. Today Chem. 35, 101833 (2024). https://doi.org/10.1016/j.mtchem.2023.101833
  139. D. Wang, J. Zhao, P. Claesson, F. Zhang, J. Pan et al., Green synergy: eco-friendly, high-performance anti-corrosion and wear-resistant coatings utilizing organosolv lignin and polydimethylsiloxane. Prog. Org. Coat. 190, 108365 (2024). https://doi.org/10.1016/j.porgcoat.2024.108365
  140. D. Chen, M. Wu, B. Li, K. Ren, Z. Cheng et al., Layer-by-layer-assembled healable antifouling films. Adv. Mater. 27(39), 5882–5888 (2015). https://doi.org/10.1002/adma.201501726
  141. L. Zhao, R. Chen, J. Liu, Q. Liu, J. Yu et al., Layer-by-layer-assembled biomimetic microstructure surface with multiple synergistic antifouling performance. Prog. Org. Coat. 183, 107812 (2023). https://doi.org/10.1016/j.porgcoat.2023.107812
  142. W. Yu, Y. Wang, P. Gnutt, R. Wanka, L.M.K. Krause et al., Layer-by-layer deposited hybrid polymer coatings based on polysaccharides and zwitterionic silanes with marine antifouling properties. ACS Appl. Bio Mater. 4(3), 2385–2397 (2021). https://doi.org/10.1021/acsabm.0c01253
  143. K. Manabe, K.-H. Kyung, S. Shiratori, Biocompatible slippery fluid-infused films composed of chitosan and alginate via layer-by-layer self-assembly and their antithrombogenicity. ACS Appl. Mater. Interfaces 7(8), 4763–4771 (2015). https://doi.org/10.1021/am508393n
  144. D. Peng, D. Deng, J. Lv, W. Zhang, H. Tian et al., A novel macroporous carboxymethyl chitosan/sodium alginate sponge dressing capable of rapid hemostasis and drug delivery. Int. J. Biol. Macromol. 278, 134943 (2024). https://doi.org/10.1016/j.ijbiomac.2024.134943
  145. J. Zhang, R. Li, S. Lv, X. Zhao, Y. Sun et al., Green manufacture of hydrated polymers coatings with on-demand mechanics and lubricity based on novel biobased polymerizable deep eutectic solvents. ACS Appl. Mater. Interfaces 17(5), 8369–8381 (2025). https://doi.org/10.1021/acsami.4c20488
  146. M.P. San Andrés, M. Baños-Cabrera, L. Gutiérrez-Fernández, A.M. Díez-Pascual, S. Vera-López, Fluorescence study of riboflavin interactions with graphene dispersed in bioactive tannic acid. Int. J. Mol. Sci. 22(10), 5270 (2021). https://doi.org/10.3390/ijms22105270
  147. Y. Gu, C. Xu, Y. Wang, J. Luo, D. Shi et al., Compressible, anti-fatigue, extreme environment adaptable, and biocompatible supramolecular organohydrogel enabled by lignosulfonate triggered noncovalent network. Nat. Commun. 16(1), 160 (2025). https://doi.org/10.1038/s41467-024-55530-1
  148. N. Lin, L. Wang, H. Tang, R. Wang, Z. Ma et al., Co-deposition of tannic acid and bottle-brush polymer to construct stable antifouling surface via hydrogen-bonding. Surf. Interfaces 53, 105010 (2024). https://doi.org/10.1016/j.surfin.2024.105010
  149. E.L. Smith, A.P. Abbott, K.S. Ryder, Deep eutectic solvents (DESs) and their applications. Chem. Rev. 114(21), 11060–11082 (2014). https://doi.org/10.1021/cr300162p
  150. Y. He, C. Chen, G. Xiao, F. Zhong, Y. Wu et al., Improved corrosion protection of waterborne epoxy/graphene coating by combining non-covalent and covalent bonds. React. Funct. Polym. 137, 104–115 (2019). https://doi.org/10.1016/j.reactfunctpolym.2019.02.001
  151. K. Tan, R. Liu, J. Luo, Y. Zhu, W. Wei et al., Tannic acid functionalized UV-curable carbon nanotube: effective reinforcement of acrylated epoxidized soybean oil coating. Prog. Org. Coat. 130, 214–220 (2019). https://doi.org/10.1016/j.porgcoat.2019.01.035
  152. H. Yang, B. Yuan, X. Zhang, O.A. Scherman, Supramolecular chemistry at interfaces: host-guest interactions for fabricating multifunctional biointerfaces. Acc. Chem. Res. 47(7), 2106–2115 (2014). https://doi.org/10.1021/ar500105t
  153. K. Huo, W. Liu, Z. Shou, H. Wang, H. Liu et al., Modulating the interactions of peptide-polyphenol for supramolecular assembly coatings with controllable kinetics and multifunctionalities. Adv. Sci. 12(3), 2412194 (2025). https://doi.org/10.1002/advs.202412194
  154. X. Zang, Y. Ni, Q. Wang, Y. Cheng, J. Huang et al., Non-toxic evolution: advances in multifunctional antifouling coatings. Mater. Today 75, 210–243 (2024). https://doi.org/10.1016/j.mattod.2024.03.018
  155. X. Liu, H.J. Zhang, S. Xi, Y. Zhang, P. Rao et al., Lignin-based ultrathin hydrogel coatings with strong substrate adhesion enabled by hydrophobic association. Adv. Funct. Mater. 35(3), 2413464 (2025). https://doi.org/10.1002/adfm.202413464
  156. A. Duval, F. Vilaplana, C. Crestini, M. Lawoko, Solvent screening for the fractionation of industrial kraft lignin. Holzforschung 70(1), 11–20 (2016). https://doi.org/10.1515/hf-2014-0346
  157. Y. Zhao, A.L. Connor, T.A. Sobiech, B. Gong, Effects of oligomer length, solvents, and temperature on the self-association of aromatic oligoamide foldamers. Org. Lett. 20(17), 5486–5489 (2018). https://doi.org/10.1021/acs.orglett.8b02438
  158. M. Yang, W. Zhao, S. Singh, B. Simmons, G. Cheng, On the solution structure of kraft lignin in ethylene glycol and its implication for nanop preparation. Nanoscale Adv. 1(1), 299–304 (2019). https://doi.org/10.1039/C8NA00042E
  159. L. Shamaei, B. Khorshidi, M.A. Islam, M. Sadrzadeh, Industrial waste lignin as an antifouling coating for the treatment of oily wastewater: creating wealth from waste. J. Clean. Prod. 256, 120304 (2020). https://doi.org/10.1016/j.jclepro.2020.120304
  160. C. Xu, L. Liu, S. Renneckar, F. Jiang, Chemically and physically crosslinked lignin hydrogels with antifouling and antimicrobial properties. Ind. Crops Prod. 170, 113759 (2021). https://doi.org/10.1016/j.indcrop.2021.113759
  161. X. Yang, J. Tang, Z. Song, W. Li, X. Gong et al., Enhancing the anti-biofouling property of solar evaporator through the synergistic antibacterial effect of lignin and nano silver. Int. J. Biol. Macromol. 268, 131953 (2024). https://doi.org/10.1016/j.ijbiomac.2024.131953
  162. Z. Wu, P.P. Thoresen, D. Maršík, L. Matsakas, M. Kulišová et al., High acetone soluble organosolv lignin extraction and its application towards green antifouling and wear-resistant coating. Int. J. Biol. Macromol. 282, 137456 (2024). https://doi.org/10.1016/j.ijbiomac.2024.137456
  163. M. Zou, Y. Ji, B. Liu, S. Liu, Q. Ye et al., Fabrication of lignin-functionalized MXene composite hydrogels with improved mechanical strength and antifouling performance. Colloids Surf. A Physicochem. Eng. Aspects 726, 137779 (2025). https://doi.org/10.1016/j.colsurfa.2025.137779
  164. D.H. Oh, J.W. Heo, M.S. Kim, Y.S. Kim, Evaluation of hydrophilicity enhancement and protein adsorption resistance of dual-amine-crosslinked lignin induced by hydration layer formation. J. Wood Chem. Technol. 45(3), 111–121 (2025). https://doi.org/10.1080/02773813.2025.2508149
  165. M. Zou, Y. Zeng, X. Wang, S. Liu, Q. Ye et al., Preparation of nanocomposite hydrogels based on zwitterionic polymer functionalized MXene nanosheets for antifouling application. Carbon 243, 120590 (2025). https://doi.org/10.1016/j.carbon.2025.120590
  166. D. Gao, W. Zhao, X. Wu, J. Hu, C. Li et al., A nanocomposite coating inspired by “mussel chemistry” and “brick-and-mortar” architecture for long-term marine antifouling and anticorrosion. ACS Appl. Mater. Interfaces 17(45), 62629–62646 (2025). https://doi.org/10.1021/acsami.5c18785
  167. X.-T. Wang, L.-Y. Liu, H. Liang, W.-Y. Ge, L.-L. Chen et al., Super stable coating based on ovalbumin and tannic acid for hydrophilic and antibacterial functionalization of polymer materials. ACS Appl. Mater. Interfaces 17(10), 16040–16056 (2025). https://doi.org/10.1021/acsami.4c21624
  168. R.K. Govindarajan, S. Revathi, N. Rameshkumar, M. Krishnan, N. Kayalvizhi, Microbial tannase: current perspectives and biotechnological advances. Biocatal. Agric. Biotechnol. 6, 168–175 (2016). https://doi.org/10.1016/j.bcab.2016.03.011
  169. N. Bellotti, B. del Amo, R. Romagnoli, Quaternary ammonium “tannate” for antifouling coatings. Ind. Eng. Chem. Res. 51(51), 16626–16632 (2012). https://doi.org/10.1021/ie301524r
  170. N. Bellotti, C. Deyá, B. del Amo, R. Romagnoli, Antifouling paints with zinc “tannate.” Ind. Eng. Chem. Res. 49(7), 3386–3390 (2010). https://doi.org/10.1021/ie9010518
  171. M. Pérez, G. Blustein, M. García, B. del Amo, M. Stupak, Cupric tannate: a low copper content antifouling pigment. Prog. Org. Coat. 55(4), 311–315 (2006). https://doi.org/10.1016/j.porgcoat.2005.11.014
  172. M. Pérez, M. García, G. Blustein, M. Stupak, Tannin and tannate from the quebracho tree: an eco-friendly alternative for controlling marine biofouling. Biofouling 23(3), 151–159 (2007). https://doi.org/10.1080/08927010701189484
  173. M.E. Stupak, M.T. Garcı́a, M.C. Pérez, Non-toxic alternative compounds for marine antifouling paints. Int. Biodeterior. Biodegrad. 52(1), 49–52 (2003). https://doi.org/10.1016/S0964-8305(03)00035-0
  174. R.S. Peres, E. Armelin, C. Alemán, C.A. Ferreira, Modified tannin extracted from black wattle tree as an environmentally friendly antifouling pigment. Ind. Crops Prod. 65, 506–514 (2015). https://doi.org/10.1016/j.indcrop.2014.10.033
  175. C. Liu, L. Wu, C. Zhang, W. Chen, S. Luo, Surface hydrophilic modification of PVDF membranes by trace amounts of tannin and polyethyleneimine. Appl. Surf. Sci. 457, 695–704 (2018). https://doi.org/10.1016/j.apsusc.2018.06.131
  176. L. Wu, Q. Lin, C. Liu, W. Chen, A stable anti-fouling coating on PVDF membrane constructed of polyphenol tannic acid, polyethyleneimine and metal ion. Polymers 11(12), 1975 (2019). https://doi.org/10.3390/polym11121975
  177. S. Moayedi, W. Xia, L. Lundergan, H. Yuan, J. Xu, Zwitterionic polymers for biomedical applications: antimicrobial and antifouling strategies toward implantable medical devices and drug delivery. Langmuir 40(44), 23125–23145 (2024). https://doi.org/10.1021/acs.langmuir.4c02664
  178. L. Carr, G. Cheng, H. Xue, S. Jiang, Engineering the polymer backbone to strengthen nonfouling sulfobetaine hydrogels. Langmuir 26(18), 14793–14798 (2010). https://doi.org/10.1021/la1028004
  179. M. Yao, X. Sun, Z. Guo, Z. Zhao, Z. Yan et al., Bioinspired zwitterionic microgel-based coating: Controllable microstructure, high stability, and anticoagulant properties. Acta Biomater. 151, 290–303 (2022). https://doi.org/10.1016/j.actbio.2022.08.022
  180. H. Dawit, S. Mehmood, Z. Hussain, S.R. Islam, Z. Wang et al., Fabrication of nanop-reinforced composite hydrogel for improved durability, antifouling, and thrombosis-resistance in arteriovenous grafts. Colloids Surf. B Biointerfaces 247, 114420 (2025). https://doi.org/10.1016/j.colsurfb.2024.114420
  181. J. Lee, I. Kim, S.M. Kang, Synergistic effect of multilayered alginate/poly(SBMA) coatings on marine antifouling property. Macromol. Biosci. 24(9), e2400130 (2024). https://doi.org/10.1002/mabi.202400130
  182. M. Yao, Z. Wei, J. Li, Z. Guo, Z. Yan et al., Microgel reinforced zwitterionic hydrogel coating for blood-contacting biomedical devices. Nat. Commun. 13(1), 5339 (2022). https://doi.org/10.1038/s41467-022-33081-7
  183. B. Song, E. Zhang, Y. Shi, W. Wang, H. Zhu et al., Zwitterionic hydrogel coating with antisediment properties for marine antifouling applications. ACS Appl. Mater. Interfaces 16(21), 27908–27916 (2024). https://doi.org/10.1021/acsami.4c02574
  184. C. Li, D. Gao, C. Li, G. Cheng, L. Zhang, Fighting against biofilm: the antifouling and antimicrobial material. Biointerphases (2024). https://doi.org/10.1116/6.0003695
  185. Y. Ma, Q. Dong, Soybean protein isolate-incorporated zwitterionic hydrogel with rapid chlorine rechargeable biocidal and antifouling functions. ACS Sustainable Chem. Eng. 11(34), 12843–12852 (2023). https://doi.org/10.1021/acssuschemeng.3c03771
  186. Y. Xiong, Z. Fang, J. Li, Z. Li, G. Wang, MXene/Ag-based zwitterionic double-network hydrogels with enhanced mechanical strength and antifouling performances. ACS Appl. Mater. Interfaces 17(2), 4231–4238 (2025). https://doi.org/10.1021/acsami.4c19096
  187. R. Wei, J. Deng, X. Guo, Y. Yang, J. Miao et al., Construction of zwitterionic coatings with lubricating and antiadhesive properties for invisible aligner applications. Macromol. Rapid Commun. 46(7), e2400234 (2025). https://doi.org/10.1002/marc.202400234
  188. P. Das, N. Durban-Benizio, S. Desclaux, C. Causserand, J.-C. Remigy et al., Light-responsive zwitterionic membrane surface modification for antifouling and antibacterial application. Chem. Eng. J. 500, 157337 (2024). https://doi.org/10.1016/j.cej.2024.157337
  189. A. Zhong, R. Tao, R. Zong, S. Liu, B. Shentu, Preparation of hydrophilic and antifouling coatings via tannic acid and zwitterionic polymers. RSC Adv. 15(10), 7248–7256 (2025). https://doi.org/10.1039/D5RA00643K
  190. Y. Liu, Y. Zhang, Q. Yang, Z. Yu, M. He et al., Tunicate cellulose nanocrystal reinforced multifunctional hydrogel with super flexible, fatigue resistant, antifouling and self-adhesive capability for effective wound healing. Int. J. Biol. Macromol. 277, 134337 (2024). https://doi.org/10.1016/j.ijbiomac.2024.134337
  191. T. Zhu, H. Cao, H. Wei, S. Zhang, Surface immobilization of sulfobetaine zwitterionic and quaternary ammonium copolymers on polyurethane surfaces to improve antifouling and bactericidal activities. Appl. Surf. Sci. 687, 162213 (2025). https://doi.org/10.1016/j.apsusc.2024.162213
  192. Z. Zhao, M. Pan, C. Qiao, L. Xiang, X. Liu et al., Bionic engineered protein coating boosting anti-biofouling in complex biological fluids. Adv. Mater. 35(6), e2208824 (2023). https://doi.org/10.1002/adma.202208824
  193. L. Wei, Y. Yang, X. Qiu, J. Shen, Y. Zhao et al., Self-polymerized tough and high-entanglement zwitterionic functional hydrogels. Small 20(50), e2405789 (2024). https://doi.org/10.1002/smll.202405789
  194. C. Sun, Y. Zhang, F. Dong, J. Zhao, P. Zhang et al., Fast-polymerized lubricant and antibacterial hydrogel coatings for medical catheters. Chem. Eng. J. 488, 150944 (2024). https://doi.org/10.1016/j.cej.2024.150944
  195. C. Wen, H. Guo, J. Yang, Q. Li, X. Zhang et al., Zwitterionic hydrogel coated superhydrophilic hierarchical antifouling floater enables unimpeded interfacial steam generation and multi-contamination resistance in complex conditions. Chem. Eng. J. 421, 130344 (2021). https://doi.org/10.1016/j.cej.2021.130344
  196. M. Nasaj, M. Chehelgerdi, B. Asghari, A. Ahmadieh-Yazdi, M. Asgari et al., Factors influencing the antimicrobial mechanism of chitosan action and its derivatives: a review. Int. J. Biol. Macromol. 277, 134321 (2024). https://doi.org/10.1016/j.ijbiomac.2024.134321
  197. H. Jang, W. Song, H. Song, D.K. Kang, S. Park et al., Sustainable biofilm inhibition using chitosan-mesoporous nanop-based hybrid slippery composites. ACS Appl. Mater. Interfaces 16(21), 27728–27740 (2024). https://doi.org/10.1021/acsami.4c03053
  198. Y. Ogawa, P.-K. Naito, Y. Nishiyama, Hydrogen-bonding network in anhydrous chitosan from neutron crystallography and periodic density functional theory calculations. Carbohydr. Polym. 207, 211–217 (2019). https://doi.org/10.1016/j.carbpol.2018.11.042
  199. E.D. Eren, G. Gu, M. Liu, B. Zhang, K. Yang et al., A novel chitosan and polydopamine interlinked bioactive coating for metallic biomaterials. J. Mater. Sci. Mater. Med. 33(10), 65 (2022). https://doi.org/10.1007/s10856-022-06688-x
  200. J. Fouilloux, S. Abbad Andaloussi, V. Langlois, L. Dammak, E. Renard, Straightforward way to provide antibacterial properties to healthcare textiles through N-2-hydroxypropyltrimethylammonium chloride chitosan crosslinking. ACS Omega 9(5), 5440–5451 (2024). https://doi.org/10.1021/acsomega.3c06832
  201. M. Hasnain, T. Kanwal, K. Rehman, S.R.U. Rehman, S. Aslam et al., Microarray needles comprised of arginine-modified chitosan/PVA hydrogel for enhanced antibacterial and wound healing potential of curcumin. Int. J. Biol. Macromol. 253(Pt 1), 126697 (2023). https://doi.org/10.1016/j.ijbiomac.2023.126697
  202. C. Sun, X. Zeng, S. Zheng, Y. Wang, Z. Li et al., Bio-adhesive catechol-modified chitosan wound healing hydrogel dressings through glow discharge plasma technique. Chem. Eng. J. 427, 130843 (2022). https://doi.org/10.1016/j.cej.2021.130843
  203. A. Vieira, L. Rodríguez-Lorenzo, A. Garrido-Maestu, B. Espiña, M. Barreiros dos Santos, Green-based modifications of polyethylene surfaces enhancing antifouling properties in water-related systems. Adv. Mater. Technol. 8(23), 2300354 (2023). https://doi.org/10.1002/admt.202300354
  204. L. Peng, L. Chang, M. Si, J. Lin, Y. Wei et al., Hydrogel-coated dental device with adhesion-inhibiting and colony-suppressing properties. ACS Appl. Mater. Interfaces 12(8), 9718–9725 (2020). https://doi.org/10.1021/acsami.9b19873
  205. R. Wang, X. Song, T. Xiang, Q. Liu, B. Su et al., Mussel-inspired chitosan-polyurethane coatings for improving the antifouling and antibacterial properties of polyethersulfone membranes. Carbohydr. Polym. 168, 310–319 (2017). https://doi.org/10.1016/j.carbpol.2017.03.092
  206. D. Kong, C. Ma, W. Wang, C. Liu, Y. Tian et al., Two birds with one stone: interfacial controls and pH response for long-term and high-efficiency Cu2O antibacterial materials. Chem. Eng. J. 427, 131734 (2022). https://doi.org/10.1016/j.cej.2021.131734
  207. S.K. Park, J.H. Shin, J.H. Jung, D.Y. Lee, D.Y. Choi et al., Polysaccharide-derivative coated intravascular catheters with superior multifunctional performance via simple and biocompatible method. Chem. Eng. J. 433, 134565 (2022). https://doi.org/10.1016/j.cej.2022.134565
  208. Z. Zhao, H. Feng, D. Qin, W. Li, W. Wang et al., pH-responsive intelligent antibacterial coatings based on 2D-COF for controlled release of capsaicin. ACS. Appl. Polym. Mater. 5(3), 2124–2135 (2023). https://doi.org/10.1021/acsapm.2c02138
  209. S. Ghattavi, E. Kamrani, A. Homaei, Green synthesis of ZnO-chitosan nanops and vinyl resin with effective antifouling properties. Prog. Org. Coat. 194, 108615 (2024). https://doi.org/10.1016/j.porgcoat.2024.108615
  210. W. Yang, M. Pan, J. Zhang, L. Zhang, F. Lin et al., A universal strategy for constructing robust and antifouling cellulose nanocrystal coating. Adv. Funct. Mater. 32(8), 2109989 (2022). https://doi.org/10.1002/adfm.202109989
  211. Y. Duan, J. Wu, W. Qi, R. Su, Eco-friendly marine antifouling coating consisting of cellulose nanocrystals with bioinspired micromorphology. Carbohydr. Polym. 304, 120504 (2023). https://doi.org/10.1016/j.carbpol.2022.120504
  212. Y. Xiong, Z. Fang, P. Tang, Y. Li, H. Jiang et al., MXene and cellulose nanofibers reinforced hydrogel with high strength and photothermal self-healing performances for marine antifouling. Carbohydr. Polym. 348, 122879 (2025). https://doi.org/10.1016/j.carbpol.2024.122879
  213. F. Long, J. Liu, X. Li, F. Sun, H. Wu et al., Bioinspired robust yet regenerable nanofibrous polymer brushes for broad-spectrum antifouling. Chem. Eng. J. 458, 141475 (2023). https://doi.org/10.1016/j.cej.2023.141475
  214. J. Zhou, Y. Duan, J. Wu, A. Penkova, R. Huang et al., Spray-drying hydrophobic cellulose nanocrystal coatings with degradable biocide release for marine antifouling. Langmuir 39(20), 7212–7220 (2023). https://doi.org/10.1021/acs.langmuir.3c00841
  215. S. Houben, L.M. Pitet, Ionic crosslinking strategies for poly(acrylamide)/alginate hybrid hydrogels. React. Funct. Polym. 191, 105676 (2023). https://doi.org/10.1016/j.reactfunctpolym.2023.105676
  216. Z. Yan, M. Yao, Z. Zhao, Q. Yang, R. Liu et al., Mechanical-enhanced and durable zwitterionic hydrogel coating for inhibiting coagulation and reducing bacterial infection. Adv. Healthc. Mater. 13(20), e2400126 (2024). https://doi.org/10.1002/adhm.202400126
  217. Y. Wang, B. Cai, D. Ni, Y. Sun, G. Wang et al., A novel antibacterial and antifouling nanocomposite coated endotracheal tube to prevent ventilator-associated pneumonia. J. Nanobiotechnol. 20(1), 112 (2022). https://doi.org/10.1186/s12951-022-01323-x
  218. F. Li, X. Han, D. Cao, J. Yin, L. Chen et al., Heat preservation, antifouling, hemostatic and antibacterial aerogel wound dressings for emergency treatment. Front. Mater. Sci. 17(2), 230641 (2023). https://doi.org/10.1007/s11706-023-0641-0
  219. Z. Lu, Z. Chen, Y. Guo, Y. Ju, Y. Liu et al., Flexible hydrophobic antifouling coating with oriented nanotopography and nonleaking capsaicin. ACS Appl. Mater. Interfaces 10(11), 9718–9726 (2018). https://doi.org/10.1021/acsami.7b19436
  220. L. Liao, Z. Ke, S. Li, S. Wang, X. Wang et al., Development of antibacterial and antifouling bio-based food packaging films using zwitterionic rosin-modified chitosan. Chem. Eng. J. 506, 159746 (2025). https://doi.org/10.1016/j.cej.2025.159746
  221. L. Wei, L. Song, Y. Yan, Y. Yu, H. Li et al., Constructing of functional hydrogel coatings via combined surface laser ablation with surface-initiated polymerization. Chem. Eng. J. 519, 164906 (2025). https://doi.org/10.1016/j.cej.2025.164906
  222. L. Zhang, M. Sun, W. Song, R. Wu, B. Yu et al., Natural macromolecule-based lubricative catheter coatings with sustained adaptive antibacterial property for encrustation and infection prevention. Adv. Healthc. Mater. 14(4), e2402359 (2025). https://doi.org/10.1002/adhm.202402359
  223. Y. Shang, P. Wang, X. Wan, L. Wang, X. Liu et al., Chlorhexidine-loaded polysulfobetaine/keratin hydrogels with antioxidant and antibacterial activity for infected wound healing. Int. J. Biol. Macromol. 242, 124754 (2023). https://doi.org/10.1016/j.ijbiomac.2023.124754
  224. E. Oguntade, L. Owuor, C. Du, A. Acierto, S. Meyer et al., Bacterial response to shape-memory actuated silk wrinkled surface topographies as a strategy for biofilm prevention. Adv. Mater. Interfaces 12(6), 2400684 (2025). https://doi.org/10.1002/admi.202400684
  225. X. Xie, J. Liu, G. Li, K. Zhang, X. Wang et al., Silk fibroin catheter with stable bioinspired inner-surfaces for inhibition of bioadhesion. Int. J. Biol. Macromol. 274, 133271 (2024). https://doi.org/10.1016/j.ijbiomac.2024.133271
  226. M. Atrian, M. Kharaziha, H. Javidan, F. Alihosseini, R. Emadi, Zwitterionic keratin coating on silk-Laponite fibrous membranes for guided bone regeneration. J. Tissue Eng. Regen. Med. 16(11), 1019–1031 (2022). https://doi.org/10.1002/term.3350
  227. D. Li, Y. Fan, G. Han, Z. Guo, Superomniphobic silk fibroin/Ag nanowires membrane for flexible and transparent electronic sensor. ACS Appl. Mater. Interfaces 12(8), 10039–10049 (2020). https://doi.org/10.1021/acsami.9b23378
  228. X. Li, Z. Yu, J. Wang, J. Zhang, W. Zhao et al., Nanomaterials reinforced antifouling coatings: from strategic design to potential applications. Adv. Mater. 38(5), e14795 (2026). https://doi.org/10.1002/adma.202514795
  229. J. Wang, R. Zhao, Z. Cheng, P. Wang, M. Jin et al., An antifouling coating based on tannic acid: an eco-friendly strategy for antioxidant removal of reactive oxygen species. J. Appl. Polym. Sci. 142(30), e57227 (2025). https://doi.org/10.1002/app.57227
  230. S.D. Mengel, J.A. Ouimet, C.K. Ober, R.A. Segalman, Spanning surface interaction length scales for the design of industrial antifouling materials. AlChE. J. 72, e70054 (2026). https://doi.org/10.1002/aic.70054
  231. H. Shi, R. Zhang, Y. Gu, Y. He, H. Wang et al., Design and application of a reversible anti-biofouling coating: Toward sustainable and reusable medical devices. Chem. Eng. J. 523, 168757 (2025). https://doi.org/10.1016/j.cej.2025.168757
  232. M. Butschle, R. Schlautek, L. Kunschert, M. Schackmann, C.E. Weinell et al., Integration of unmodified kraft lignin powder in waterborne coatings and investigation of antifouling properties. J. Coat. Technol. Res. 21(3), 993–1003 (2024). https://doi.org/10.1007/s11998-023-00867-3
  233. H.-H. Hao, P. Liu, P. Su, T. Chen, M. Zhu et al., Sea-trial research on natural product-based antifouling paint applied to different underwater sensor housing materials. Int. Biodeterior. Biodegrad. 170, 105400 (2022). https://doi.org/10.1016/j.ibiod.2022.105400
  234. J. Zhang, X. Bai, R. Chen, J. Yu, P. Liu et al., Bionic transparent antifouling coatings with linalool inspired by Salvia: investigating the inhibition mechanism on typical fouling organism. Prog. Org. Coat. 196, 108679 (2024). https://doi.org/10.1016/j.porgcoat.2024.108679
  235. Y. Zhang, L. Chen, Z. Lin, L. Ding, X. Zhang et al., Highly sensitive dissolved oxygen sensor with a sustainable antifouling, antiabrasion, and self-cleaning superhydrophobic surface. ACS Omega 4(1), 1715–1721 (2019). https://doi.org/10.1021/acsomega.8b02464
  236. W.K. Szapoczka, V.H. Larsen, H. Böpple, D.M.M. Kleinegris, Z. Diao et al., Transparent, antibiofouling window obtained with surface nanostructuring. ACS Omega, acsomega.4c03030 (2024). https://doi.org/10.1021/acsomega.4c03030
  237. L. Delauney, C. Compère, M. Lehaitre, Biofouling protection for marine environmental sensors. Ocean Sci. 6(2), 503–511 (2010). https://doi.org/10.5194/os-6-503-2010
  238. T. Jiang, L. Qi, W. Qin, Improving the environmental compatibility of marine sensors by surface functionalization with graphene oxide. Anal. Chem. 91(20), 13268–13274 (2019). https://doi.org/10.1021/acs.analchem.9b03974
  239. J. Wang, X. Li, L. Zheng, Y. Li, Biofouling prevention and control technology for marine engineering equipment: from traditional methods to intelligent interface engineering. Mar. Pollut. Bull. 223, 118924 (2026). https://doi.org/10.1016/j.marpolbul.2025.118924
  240. Y. Long, Y. Yu, X. Yin, J. Li, C. Carlos et al., Effective anti-biofouling enabled by surface electric disturbance from water wave-driven nanogenerator. Nano Energy 57, 558–565 (2019). https://doi.org/10.1016/j.nanoen.2018.12.069
  241. P.A. Hoeher, O. Zenk, B. Cisewski, K. Boos, J. Groeger, UVC-based biofouling suppression for long-term deployment of underwater cameras. IEEE J. Ocean. Eng. 48(4), 1389–1405 (2023). https://doi.org/10.1109/JOE.2023.3265164
  242. X. Wang, Q. Jiang, D. Han, Y. Chen, W. Liu et al., Progress in anti-biofouling materials and coatings for the marine environment. J. Environ. Sci. 161, 494–510 (2026). https://doi.org/10.1016/j.jes.2025.05.038
  243. W.A. Laftah, W.A. Wan Abdul Rahman, Polymers for anti-fouling applications: a review. Environ. Sci. Adv. 4(6), 824–841 (2025). https://doi.org/10.1039/d5va00034c
  244. H. Lin, Y. Li, R. He, W. Zheng, Y. Lai et al., Fabrication of large-area, ultra-strong, and anti-swelling hydrogel thin films for underwater invisible electronic skin. Adv. Funct. Mater. 35(47), 2507606 (2025). https://doi.org/10.1002/adfm.202507606
  245. J. Ladd, Z. Zhang, S. Chen, J.C. Hower, S. Jiang, Zwitterionic polymers exhibiting high resistance to nonspecific protein adsorption from human serum and plasma. Biomacromol 9(5), 1357–1361 (2008). https://doi.org/10.1021/bm701301s
  246. G. Parada, Y. Yu, W. Riley, S. Lojovich, D. Tshikudi et al., Ultrathin and robust hydrogel coatings on cardiovascular medical devices to mitigate thromboembolic and infectious complications. Adv. Healthc. Mater. 9(20), e2001116 (2020). https://doi.org/10.1002/adhm.202001116
  247. J. Liu, J. Liu, Y. Liang, J. Yang, Y. Lin et al., Microneedle-based electrochemical array patch for ultra-antifouling and ultra-anti-interference monitoring of subcutaneous oxygen. Anal. Chem. 97(1), 373–381 (2025). https://doi.org/10.1021/acs.analchem.4c04345
  248. Y. Ouyang, X. Su, X. Zheng, L. Zhang, Z. Chen et al., Mussel-inspired “all-in-one” sodium alginate/carboxymethyl chitosan hydrogel patch promotes healing of infected wound. Int. J. Biol. Macromol. 261, 129828 (2024). https://doi.org/10.1016/j.ijbiomac.2024.129828
  249. J. Huang, H. Yuan, B. Qian, X. Zhang, M. Lan, Polyurethane surface with antibacterial and antifouling properties enabled via surface grafting of imidazolium salt chitosan graft-polyzwitterionic copolymer. ACS. Appl. Polym. Mater. 6(19), 11840–11849 (2024). https://doi.org/10.1021/acsapm.4c01908
  250. Y. Jiang, X. Zhang, Infant skin friendly adhesive hydrogel patch activated at body temperature for bioelectronics securing and diabetic wound healing. 16(6), 8662–8676 (2022). https://doi.org/10.1021/acsnano.2c00662
  251. J. Wellens, O. Deschaume, T. Putzeys, S. Eyley, W. Thielemans et al., Sulfobetaine-based ultrathin coatings as effective antifouling layers for implantable neuroprosthetic devices. Biosens. Bioelectron. 226, 115121 (2023). https://doi.org/10.1016/j.bios.2023.115121
  252. S. Manoharan, P. Balakrishnan, L.K. Sellappan, A. Sanmugam, Green synthesized cerium oxide nanops incorporated chitosan-alginate based nanobiopatch for enhanced antibacterial wound dressing applications. J. Drug. Deliv. Sci. Technol. 108, 106892 (2025). https://doi.org/10.1016/j.jddst.2025.106892
  253. Y. Cheng, Y. Wang, Y. Wang, P.-C. Tan, S. Yu et al., Microenvironment-feedback regulated hydrogels as living wound healing materials. Nat. Commun. 16(1), 6050 (2025). https://doi.org/10.1038/s41467-025-60858-3
  254. J.F. Mujica-Alarcon, J. Gomez-Bolivar, J. Barnes, M. Chronopoulou, J.J. Ojeda et al., The influence of surface materials on microbial biofilm formation in aviation fuel systems. Biofouling 41(3), 265–282 (2025). https://doi.org/10.1080/08927014.2025.2471366
  255. Z. Song, R. Han, K. Yu, R. Li, X. Luo, Antifouling strategies for electrochemical sensing in complex biological media. Mikrochim. Acta 191(3), 138 (2024). https://doi.org/10.1007/s00604-024-06218-2
  256. A.C. Zambrano, L.M.D. Loiola, A. Bukhamsin, R. Gorecki, G. Harrison et al., Porous laser-scribed graphene electrodes modified with zwitterionic moieties: a strategy for antibiofouling and low-impedance interfaces. ACS Appl. Mater. Interfaces 16(4), 4408–4419 (2024). https://doi.org/10.1021/acsami.3c15849
  257. J.C. Lee, S.Y. Kim, J. Song, H. Jang, M. Kim et al., Micrometer-thick and porous nanocomposite coating for electrochemical sensors with exceptional antifouling and electroconducting properties. Nat. Commun. 15, 711 (2024). https://doi.org/10.1038/s41467-024-44822-1
  258. M. Wang, J. Hu, M. Li, L. Zhang, M. Salimi et al., Bioinspired design of photothermal anti-fouling fabrics for solar-driven sustainable seawater desalination. Nano Energy 136, 110726 (2025). https://doi.org/10.1016/j.nanoen.2025.110726
  259. Y.-H. Ju, T.-Y. Hsieh, Y.-H. Lin, C.-L. Liu, D.-Y. Kang et al., Hybrid MOF-zwitterionic polymer membranes for efficient and antifouling solar seawater desalination. ACS Appl. Polym. Mater. 7(18), 12211–12219 (2025). https://doi.org/10.1021/acsapm.5c01693
  260. Z. Yan, D. Zhou, Q. Zhang, Y. Zhu, Z. Wu, A critical review on fouling influence factors and antifouling coatings for heat exchangers of high-salt industrial wastewater. Desalination 553, 116504 (2023). https://doi.org/10.1016/j.desal.2023.116504
  261. L. Wang, P.V. Kelly, N. Ozveren, X. Zhang, M. Korey et al., Multifunctional polymer composite coatings and adhesives by incorporating cellulose nanomaterials. Matter 6(2), 344–372 (2023). https://doi.org/10.1016/j.matt.2022.11.024
  262. K. Sabet-Bokati, K. Plucknett, Water-induced failure in polymer coatings: mechanisms, impacts and mitigation strategies: a comprehensive review. Polym. Degrad. Stab. 230, 111058 (2024). https://doi.org/10.1016/j.polymdegradstab.2024.111058
  263. K. Enomoto, S. Takahashi, T. Iwase, T. Yamashita, Y. Maekawa, Degradation manner of polymer grafts chemically attached on thermally stable polymer films: swelling-induced detachment of hydrophilic grafts from hydrophobic polymer substrates in aqueous media. J. Mater. Chem. 21(25), 9343–9349 (2011). https://doi.org/10.1039/C0JM04084C
  264. K. Rasmussen, G. Grampp, M. van Eesbeek, T. Rohr, Thermal and UV degradation of polymer films studied in situ with ESR spectroscopy. ACS Appl. Mater. Interfaces 2(7), 1879–1883 (2010). https://doi.org/10.1021/am100219z
  265. Z. Zhang, R. Chen, J. Yu, G. Sun, Q. Liu et al., Fluorocarbon-based self-layering interpenetrating polymer-network coatings with anti-fouling and anti-icing properties. Chem. Eng. J. 474, 145540 (2023). https://doi.org/10.1016/j.cej.2023.145540
  266. X. Li, S. Fan, J. Ma, Z. Zhu, D. Guan et al., Tough, highly resilient and fatigue-resistant cellulose-based double-network elastomers with environmental tolerance for multi-domain sensing. Chem. Eng. J. 523, 168273 (2025). https://doi.org/10.1016/j.cej.2025.168273
  267. J. Hu, D. Zhang, W. Li, Y. Li, G. Shan et al., Construction of a soft antifouling PAA/PSBMA hydrogel coating with high toughness and low swelling through the dynamic coordination bonding provided by Al(OH)3 nanops. ACS Appl. Mater. Interfaces 16(5), 6433–6446 (2024). https://doi.org/10.1021/acsami.3c17580
  268. J. Pan, X. Liu, X. Cao, X. Ma, Y. Hu et al., Anti-bioadhesive polyurethane coatings enhanced by salicylic acid-carboxy-betaine modified nano-silica: stepwise antifouling mechanism. Prog. Org. Coat. 187, 108161 (2024). https://doi.org/10.1016/j.porgcoat.2023.108161
  269. J. Sun, X. Liu, J. Duan, K. Sui, X. Zhai et al., A type of multifunctional cellulose nanocrystal composite silicone-based polymer coating for marine antibiofouling. Int. J. Biol. Macromol. 278, 134885 (2024). https://doi.org/10.1016/j.ijbiomac.2024.134885
  270. Y. Xie, S. Wu, H. Liu, Y. Zheng, K. Zhao et al., High-performance anti-fouling coating: Achieving high transparency, durability, and flexibility via epoxy-amine curing with dense cross-linking design. J. Mater. Sci. Technol. 242, 255–263 (2026). https://doi.org/10.1016/j.jmst.2025.03.097
  271. J. Sun, J. Duan, C. Liu, X. Liu, Y. Zhu et al., Transparent and mechanically durable silicone/ZrO2 sol hybrid coating with enhanced antifouling properties. Chem
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