Issue

Vol. 17 (2025)

Exploring Single-Atom Nanozymes Toward Environmental Pollutants: Monitoring and Control

https://doi.org/10.1007/s40820-025-01734-z
Guojian Wu
Engineering Research Center of Bio‑Process, Ministry of Education, School of Food & Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China
Si Li
Engineering Research Center of Bio‑Process, Ministry of Education, School of Food & Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China
Linpin Luo
College of Food Science and Engineering, Northwest A & F University, Yangling 712100, People’s Republic of China
Yuechun Li
College of Food Science and Engineering, Northwest A & F University, Yangling 712100, People’s Republic of China
Wentao Zhang
College of Food Science and Engineering, Northwest A & F University, Yangling 712100, People’s Republic of China
Heng Wang
Engineering Research Center of Bio‑Process, Ministry of Education, School of Food & Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China
Sha Liu
Engineering Research Center of Bio‑Process, Ministry of Education, School of Food & Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China
Chenxing Du
Engineering Research Center of Bio‑Process, Ministry of Education, School of Food & Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China
Jianlong Wang
College of Food Science and Engineering, Northwest A & F University, Yangling 712100, People’s Republic of China
Jie Cheng
Institute of Quality Standards and Testing Technologies for Agro‑Products, Chinese Academy of Agricultural Sciences, Beijing 100081, People’s Republic of China
Yongning Wu
NHC Key Lab of Food Safety Risk Assessment, Research Unit of Food Safety, China National Center for Food Safety Risk Assessment (CFSA), Chinese Academy of Medical Sciences (No. 2019RU014), Beijing 100022, People’s Republic of China
Yizhong Shen
Engineering Research Center of Bio‑Process, Ministry of Education, School of Food & Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China

Corresponding Author: Yizhong Shen

yzshen@hfut.edu.cn

Nano-Micro Letters, Vol. 17 (2025), Article Number: 238

Abstract

As environmental pollutants pose a serious threat to socioeconomic and environmental health, the development of simple, efficient, accurate and cost-effective methods for pollution monitoring and control remains a major challenge, but it is an unavoidable issue. In the past decade, the artificial nanozymes have been widely used for environmental pollutant monitoring and control, because of their low cost, high stability, easy mass production, etc. However, the conventional nanozyme technology faces significant challenges in terms of difficulty in regulating the exposed crystal surface, complex composition, low catalytic activity, etc. In contrast, the emerging single-atom nanozymes (SANs) have attracted much attention in the field of environmental monitoring and control, due to their multiple advantages of atomically dispersed active sites, high atom utilization efficiency, tunable coordination environment, etc. To date, the insufficient efforts have been made to comprehensively characterize the applications of SANs in the monitoring and control of environmental pollutants. Building on the recent advances in the field, this review systematically summarizes the main synthesis methods of SANs and highlights their advances in the monitoring and control of environmental pollutants. Finally, we critically evaluate the limitations and challenges of SANs, and provide the insights into their future prospects for the monitoring and control of environmental pollutants.


Highlights:
1 Review of the state-of-the-art synthesis strategies for single-atom nanozymes.
2 Analysis of the recent advances in single-atom nanozymes for monitoring and control of environmental pollutants.
3 Challenges and perspectives of single-atom nanozymes in environmental pollutants monitoring and control.

Keywords

Single-atom nanozyme Environmental health Environmental pollutant Monitoring Control
Wu, Guojian, Si Li, Linpin Luo, Yuechun Li, Wentao Zhang, Heng Wang, Sha Liu, Chenxing Du, Jianlong Wang, Jie Cheng, Yongning Wu, and Yizhong Shen. 2025. “Exploring Single-Atom Nanozymes Toward Environmental Pollutants: Monitoring and Control”. Nano-Micro Letters 17 (April):238. https://doi.org/10.1007/s40820-025-01734-z.
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