Issue

Vol. 18 (2026)

Unveiling Photo-Thermal-Electrical Performance in Robust, Self-Healing, and Anti-Freezing Cellulose-MXene Eutectogels for Advanced Hemostasis

https://doi.org/10.1007/s40820-026-02283-9
Chuang Jiang
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Hengli Ning
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Wei Liu
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Zhikun Li
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Huiwu Zhu
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Long Li
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Qingxi Hou
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China
Chaoji Chen
Hubei Biomass‑Resource Chemistry and Environmental Biotechnology Key Laboratory, Hubei Provincial Engineering Research Center of Emerging Functional Coating Materials, School of Resource and Environmental Sciences, Wuhan University, Wuhan 430079, People’s Republic of China
Bowen Cheng
State Key Laboratory of Bio‑Based Fiber Materials, China Textile Industry Key Laboratory of High‑Performance Fibers Wet‑Laid Nonwoven Materials, Tianjin Key Laboratory of Pulp & Paper, Tianjin University of Science and Technology, Tianjin 300457, People’s Republic of China

Corresponding Author: Bowen Cheng

bowenc15@tust.edu.cn

Nano-Micro Letters, Vol. 18 (2026), Article Number: 444

Abstract

Uncontrolled hemorrhage, resulting from trauma or surgery, presents a critical challenge in medical care. This study introduces a novel eutectogel, a multifunctional material synthesized using choline chloride/phytic acid derived deep eutectic solvents (CP-DES)-mediated cellulose-MXene polyacrylamide, aimed at addressing hemostatic needs. The eutectogel combines photothermal and thermoelectric effects to accelerate hemorrhage control, significantly reducing blood loss and hemostasis time. Unlike existing hemostatic materials, our design leverages the synergistic effects of photothermal heating and thermoelectric current, enhancing coagulation and promoting tissue repair. The innovation lies in the integration of DES to stabilize MXene, optimizing its photothermal and thermoelectric properties, and enabling rapid gelation, self-healing, and anti-freezing capabilities. In vitro and in vivo tests demonstrate the material’s superior performance in hemostasis compared to traditional gauze, highlighting its potential for trauma care and surgical applications. This approach sets a new paradigm in the development of advanced, multifunctional biomedical materials for hemostasis and beyond.


Highlights:
1 A deep eutectic solvent-mediated strategy integrates cellulose and MXene into a polyacrylamide network, enabling rapid gelation, and long-term MXene stabilization (>690 days).
2 The eutectogel exhibits tissue-adhesive, self-healing, anti-freezing properties, high ionic conductivity, and efficient photothermal conversion, enabling multimodal sensing and synergistic photothermoelectric hemostasis.
3 First demonstration of synergistic photothermoelectric hemostasis, where localized photothermal heating and Seebeck-driven microcurrents synergistically accelerate coagulation, achieving superior hemostatic performance with significantly reduced blood loss and hemostasis time.

Keywords

Cellulose Deep eutectic solvents MXene Photothermoelectric eutectogel Hemostasis
Jiang, Chuang, Hengli Ning, Wei Liu, Zhikun Li, Huiwu Zhu, Long Li, Qingxi Hou, Chaoji Chen, and Bowen Cheng. 2026. “Unveiling Photo-Thermal-Electrical Performance in Robust, Self-Healing, and Anti-Freezing Cellulose-MXene Eutectogels for Advanced Hemostasis”. Nano-Micro Letters 18 (July):444. https://doi.org/10.1007/s40820-026-02283-9.
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